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Muscarinic stimulation of phospholipid turnover in dissociated avian salt gland cells.

作者信息

Fisher S K, Hootman S R, Heacock A M, Ernst S A, Agranoff B W

出版信息

FEBS Lett. 1983 May 2;155(1):43-6. doi: 10.1016/0014-5793(83)80205-1.

DOI:10.1016/0014-5793(83)80205-1
PMID:6840282
Abstract

Addition of carbamylcholine to 32P-prelabeled dissociated avian salt gland cells resulted in increased turnover of phosphatidic acid, phosphatidylinositol, phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate, which could be prevented by the inclusion of atropine. Carbamylcholine had no discernable effect on protein phosphorylation, measured either in the total preparation or in subcellular fractions. It is concluded that for the avian salt gland, no obligatory link is indicated between protein phosphorylation and either phospholipid turnover or salt secretion.

摘要

相似文献

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引用本文的文献

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Muscarinic-receptor activation stimulates oscillations in K+ and Cl- currents which are acutely dependent on extracellular Ca2+ in avian salt gland cells.毒蕈碱受体激活可刺激钾离子和氯离子电流振荡,这些振荡在鸟类盐腺细胞中急性依赖于细胞外钙离子。
Pflugers Arch. 1994 Feb;426(3-4):231-8. doi: 10.1007/BF00374776.
2
Lysophosphatidic acid induces inositol phosphate and calcium signals in exocrine cells from the avian nasal salt gland.
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Inositol trisphosphate and diacylglycerol as second messengers.肌醇三磷酸和二酰甘油作为第二信使。
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Biochem J. 1992 Mar 15;282 ( Pt 3)(Pt 3):703-10. doi: 10.1042/bj2820703.