O'Brien W F, Cefalo R C, Davis S E, Ramwell P W
Eur J Obstet Gynecol Reprod Biol. 1983 Feb;14(5):317-21. doi: 10.1016/0028-2243(83)90007-2.
Prostaglandins have been detected in high levels in the fetal circulation. These substances are known to cause marked changes in the fetal and uterine circulations. The present study demonstrated an increase in fetal and maternal circulating levels of i prostaglandin F2 alpha in fetal lambs with acute acidosis. Both levels correlated with the degree of fetal acidosis. No consistent change in levels of i PGE were noted. Prostaglandins may play a role in the pathogenesis of response to fetal stress.
在胎儿循环中已检测到高水平的前列腺素。已知这些物质会引起胎儿和子宫循环的显著变化。本研究表明，患有急性酸中毒的胎羊中，胎儿和母体循环中的前列腺素F2α水平升高。这两个水平都与胎儿酸中毒的程度相关。未观察到前列腺素E水平的一致变化。前列腺素可能在胎儿应激反应的发病机制中起作用。
