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[下肢急性缺血的病因]

[Etiology of acute ischemia of the lower limbs].

作者信息

Hodara M

出版信息

J Mal Vasc. 1983;8(1):101-5.

PMID:6842090
Abstract

The most frequent cause of acute ischaemia of the lower limbs is arterial: thrombotic, embolic and spastic. In cases of arterial embolism, the site of origin is the left side of the heart in 9 cases out of 10: ischaemic heart disease in 2/3 of cases, with atrial fibrillation (A.F.) in 50% of cases, rheumatic valvular disease with A.F. in 1/5 of cases and more rarely, idiopathic A.F., auricular disease and cardiomyopathies. Arterial emboli can be fragments from a wall thrombus (aortic or arterial aneurysm), or atheromatous material from an ulcerated plaque. In 11% of cases the origin of the embolus is never found. Arterial thrombosis is due to chronic vascular disease in 1/3 of cases, popliteal aneurysm and thromboangiitis obliterans. The iatrogenic causes are rare: use of the arterial route, and arterial prosthesis, accidental intra-arterial injection during sclerotherapy for varicose veins. Arterial spasm is seen in cases of phlegmatia caerulea dolens. It ben be iatrogenic (ergotamine tartrate, dihydroergotamine, methysergide), toxic (L.S.D.) or spontaneous.

摘要

下肢急性缺血最常见的原因是动脉性的

血栓形成、栓塞和痉挛。在动脉栓塞病例中,十分之九的栓子起源于心脏左侧:三分之二的病例患有缺血性心脏病,其中50%伴有心房颤动(房颤),五分之一的病例患有风湿性瓣膜病并伴有房颤,更罕见的是特发性房颤、耳部疾病和心肌病。动脉栓子可以是壁血栓(主动脉或动脉瘤)的碎片,也可以是溃疡斑块的粥样物质。11%的病例栓子来源始终不明。三分之一的动脉血栓形成病例是由慢性血管疾病、腘动脉瘤和血栓闭塞性脉管炎引起的。医源性原因较为罕见:动脉途径的使用、动脉假体、静脉曲张硬化治疗期间意外的动脉内注射。在蓝色血栓性静脉炎病例中可见动脉痉挛。它可能是医源性的(酒石酸麦角胺、二氢麦角胺、甲基麦角新碱)、中毒性的(麦角酸二乙胺)或自发性的。

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