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[下肢急性缺血的心脏病因]

[Cardiac causes of acute ischemia of lower limbs].

作者信息

Heulin A, Fleury G

出版信息

Phlebologie. 1978 Apr-Jun;31(2):135-9.

PMID:693586
Abstract

Acute ischemias of the legs of cardiac origin are almost always due to leg embolus caused by fragmentation of an endoauricular or left venticular thrombosis. The two main causes are easily recognized: mitral narrowing and ventricular aneurysm are seldom accompanied by seeding, because a prophylactic treatment with anti-vitamin K is started as soon as the diagnosis is made. Use of prosthetic valves, despite constant improvement in their manufacture and systematic administration of anticoagulant drugs, are always complicated by embolisms (4 to 7% of cases at present). On the other hand, two causes of leg embolisms should be carefully sought since they give rise to revealing seedings. Non-obstructive cardiomyopathy gives a picture of primitive cardiac insufficiency developing progressively. Paroxysmal supraventricular rhythm disorders may be completely overlooked, and only an electrocardiogram continued during 24 hours allows their detection. Embolisms which do not involve the legs, are secondary. Seeding of a chalky fragment from a stenotic aortic valve is very rare. On the other hand, embolisms of anauricular fragment of myxoma and especially membranous embolisms during infectious endocarditis, are not so rare.

摘要

心脏源性腿部急性缺血几乎总是由心耳或左心室血栓碎裂导致的腿部栓子引起。两个主要原因很容易识别:二尖瓣狭窄和心室壁瘤很少伴有血栓形成,因为一旦确诊就会立即开始使用抗维生素K进行预防性治疗。尽管人工瓣膜的制造不断改进且系统地使用了抗凝药物,但仍总是伴有栓塞并发症(目前病例的4%至7%)。另一方面,应仔细寻找腿部栓塞的两个原因,因为它们会引发有提示意义的血栓形成。非梗阻性心肌病表现为逐渐发展的原发性心脏功能不全。阵发性室上性心律失常可能完全被忽视,只有持续24小时的心电图才能检测到它们。不涉及腿部的栓塞是继发性的。来自狭窄主动脉瓣的白垩样碎片的血栓形成非常罕见。另一方面,黏液瘤的心耳碎片栓塞,尤其是感染性心内膜炎期间的膜性栓塞,并不罕见。

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