Azibi M, Draguet-Brughmans M, Bouche R, Tinant B, Germain G, Declercq J P, Van Meerssche M
J Pharm Sci. 1983 Mar;72(3):232-5. doi: 10.1002/jps.2600720308.
A second polymorph of spiperone, 8-[3-(p-fluorobenzoyl)-propyl]-1-phenyl-1,3,8-triazaspiro[4,5] decan-4-one, has been isolated and characterized by thermal analysis and IR spectrometry. Its structure was solved by X-ray diffraction analysis. The results are compared with those previously obtained on spiperone, the main difference being in the conformation of the side chain and in the nature of the hydrogen bonding.
已分离出螺哌隆的第二种多晶型物8-[3-(对氟苯甲酰基)-丙基]-1-苯基-1,3,8-三氮杂螺[4,5]癸烷-4-酮，并通过热分析和红外光谱对其进行了表征。通过X射线衍射分析确定了其结构。将结果与先前在螺哌隆上获得的结果进行了比较，主要差异在于侧链的构象和氢键的性质。
