苯巴比妥与硫利达嗪在人体中的相互作用。
Phenobarbital--thioridazine interaction in man.
作者信息
Ellenor G L, Musa M N, Beuthin F C
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Jul;21(1):185-8.
PMID:684278
Abstract
Plasma thioridazine levels were estimated in seven retarded patients during the course of gradual phenobarbital withdrawal. In each patient, plasma levels of thioridazine plus metabolites increased with decreasing phenobarbital dose. Possible mechanisms of the interaction are discussed.
摘要
在逐渐停用苯巴比妥的过程中，对7名智力迟钝患者的血浆硫利达嗪水平进行了评估。在每名患者中，硫利达嗪及其代谢产物的血浆水平随着苯巴比妥剂量的减少而升高。文中讨论了这种相互作用的可能机制。
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