Shipilova T V
Kardiologiia. 1983 Feb;23(2):85-8.
During 3 years cholesterol, triglyceride and lipoprotein levels were repeatedly determined in the blood of 125 patients with coronary disease, and the severity of the disease was assessed with bicycle ergometry and coronarography. A relationship has been established between the severity of the disease and its course and the degree of disorders in the lipid metabolism. Group with stable normolipidemia (28%) showed less manifest symptoms of the disease and absence of rapid progression with new coronary accidents. Groups with hyperlipoproteinemia both stable (52.8%) and transient (19.2%) had predominantly severe forms of the disease running unfavourable course. The more frequent with severe and extended, according to angiography atherosclerosis of the coronaries and unfavourable course of disease were associated with hyperlipoproteinemia type II.
在3年期间，对125例冠心病患者的血液进行了多次胆固醇、甘油三酯和脂蛋白水平测定，并用自行车测力计和冠状动脉造影评估疾病的严重程度。已确定疾病的严重程度及其病程与脂质代谢紊乱程度之间存在关联。血脂正常稳定组（28%）的疾病症状表现较轻，且无新的冠状动脉意外快速进展情况。高脂血症稳定组（52.8%）和短暂性高脂血症组（19.2%）的疾病主要为严重形式，病程不利。根据血管造影，冠状动脉严重且广泛的动脉粥样硬化以及疾病的不利病程在II型高脂血症中更为常见。
