Krivoruchenko I V, Nikul'cheva N G, Kukuĭ L M, Bermiakova A S, Triufanov V F
Kardiologiia. 1979 Apr;19(4):67-73.
The blood lipid content and lipoprotein spectrum were repeatedly tested in 216 males with ischemic heart disease for follow-up periods of 4 to 5 years. Irrespective of the type of hyperlipoproteinemia, the blood triglyceride level was marked by the greatest individual fluctuations and the level of total cholesterol by the least fluctuations. Comparison of the clinical course of ischemic heart disease with the peculiarities of the changes in the blood lipid content revealed a higher incidence of recurrent myocardial infarction and sudden death among individuals with type IIa hyperlipoproteinemia. Recurrent vascular catastrophes were observed not only in patients with stable hypercholesterolemia but also in individuals with its labile form. It is concluded that repeated tests for the blood lipid content provide for more reliable diagnosis of hyperlipidemia and the type of hyperlipoproteinemia, which is of unquestionable practical importance.
对216名患有缺血性心脏病的男性进行了4至5年的随访，期间反复检测其血脂含量和脂蛋白谱。无论高脂蛋白血症的类型如何，血液甘油三酯水平的个体波动最大，而总胆固醇水平的波动最小。将缺血性心脏病的临床病程与血脂含量变化的特点进行比较后发现，IIa型高脂蛋白血症患者中复发性心肌梗死和猝死的发生率较高。不仅在患有稳定型高胆固醇血症的患者中观察到复发性血管灾难，在不稳定型高胆固醇血症患者中也观察到了。得出的结论是，反复检测血脂含量有助于更可靠地诊断高脂血症和高脂蛋白血症的类型，这具有毋庸置疑的实际重要性。
