Nikul'cheva N G, Krivoruchenko I V, Bermiakova A S, Kukuĭ L M, Arkhipov O P
Kardiologiia. 1980 Aug;20(8):15-20.
The authors conducted a repeated examination of 150 patients suffering from ischemic heart disease with normolipidemia and types IIa, IIb and IV hyperlipoproteinemia. The content of alpha-cholesterol in these patients tended to fluctuate, just as the content of other blood lipid fractions. Its fluctuations were most marked in types 11b and IV hyperlipoproteinemia. Comparison of the alpha-cholesterol content in patients with ischemic heart disease with the results of population tests confirmed the information on its lower level in patients. A still greater difference between patients and healthy individuals was revealed when the percentage of total cholesterol for which alpha-lipoproteines accounted and the value of the cholesterol atherogenic index were compared. Reduced concentration of alpha-cholesterol was encountered not only in hyperlipoproteinemia, but also in normolipidemia. The level of alpha-cholesterol had a negative correlative connection with the content of triglycerides in the blood.
作者对150例患有缺血性心脏病且血脂正常以及患有IIa型、IIb型和IV型高脂蛋白血症的患者进行了反复检查。这些患者体内α - 胆固醇的含量往往会波动,其他血脂成分的含量也是如此。其波动在IIb型和IV型高脂蛋白血症中最为明显。将缺血性心脏病患者的α - 胆固醇含量与群体检测结果进行比较,证实了患者体内该物质水平较低的信息。当比较α - 脂蛋白占总胆固醇的百分比以及胆固醇致动脉粥样硬化指数的值时,患者与健康个体之间的差异更为显著。不仅在高脂蛋白血症中,而且在血脂正常的情况下,都发现α - 胆固醇浓度降低。α - 胆固醇水平与血液中甘油三酯的含量呈负相关。