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光纤引导激光进入大鼠脑内对条件性回避反应和脑化学的影响。

Effects of laser guided by optic fiber into rat brain on conditioned avoidance response and brain chemistry.

作者信息

Lin S Z, Wang L H

出版信息

Lasers Surg Med. 1983;2(3):231-9. doi: 10.1002/lsm.1900020306.

Abstract

Low power lasers were guided by optic fibers into the rat caudate nucleus or frontal cortex, during conditioned avoidance response (CAR) training. The changes in striatal monoamine and amino acid concentrations were subsequently determined. Of six training groups tested, only the experimental group with helium-neon laser radiation to the caudate nucleus exhibited the formation of CAR and an increase of unconditioned leg contractions. The striatal concentrations of dopamine (DA) and norepinephrine (NE) were increased simultaneously in the group.

摘要

在条件性回避反应(CAR)训练期间,低功率激光通过光纤导入大鼠尾状核或额叶皮质。随后测定纹状体中单胺和氨基酸浓度的变化。在测试的六个训练组中,只有用氦氖激光照射尾状核的实验组表现出CAR的形成以及非条件性腿部收缩的增加。该组中多巴胺(DA)和去甲肾上腺素(NE)的纹状体浓度同时升高。

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