赖氨酸茶碱（一种新型可溶性茶碱）在人体志愿者中的药代动力学。
The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.
作者信息
Johnston A, Aldhous M E, Hedges A, Weerasuriya K, Freedman A, Turner P
出版信息
Postgrad Med J. 1983 Feb;59(688):86-7. doi: 10.1136/pgmj.59.688.86.
Abstract
A comparative study of the pharmacokinetics of lysine theophylline and aminophylline in normal subjects reveals no significant difference. If lysine theophylline is shown to have the same clinical efficacy as aminophylline, the hypersensitivity reactions associated with the latter could be avoided.
摘要
一项针对正常受试者的赖氨酸茶碱和氨茶碱药代动力学的对比研究显示，二者并无显著差异。若赖氨酸茶碱被证明与氨茶碱具有相同的临床疗效，那么与氨茶碱相关的过敏反应便可避免。
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The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.赖氨酸茶碱（一种新型可溶性茶碱）在人体志愿者中的药代动力学。
Postgrad Med J. 1983 Feb;59(688):86-7. doi: 10.1136/pgmj.59.688.86.
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Br J Clin Pharmacol. 1984 Aug;18(2):258-62. doi: 10.1111/j.1365-2125.1984.tb02466.x.
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Eur J Clin Pharmacol. 1985;29(2):177-9. doi: 10.1007/BF00547418.
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本文引用的文献
1
Theophylline pharmacokinetics in advanced age.老年人的茶碱药代动力学。
Br J Clin Pharmacol. 1981 Nov;12(5):637-45. doi: 10.1111/j.1365-2125.1981.tb01282.x.
2
Immediate hypersensitivity reaction to aminophylline. Report of a case with immunologic confirmation by an in vitro procedure.对氨茶碱的速发型超敏反应。一例经体外检测获得免疫学确诊的病例报告。
J Allergy Clin Immunol. 1971 Sep;48(3):165-70. doi: 10.1016/0091-6749(71)90012-1.
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The epidemiology of contact dermatitis in Poland.波兰接触性皮炎的流行病学
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Contact dermatitis attributed to ethylenediamine.乙二胺所致接触性皮炎
Br Med J. 1978 Feb 18;1(6110):415-6. doi: 10.1136/bmj.1.6110.415.
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Urticaria following intravenous aminophylline.静脉注射氨茶碱后出现荨麻疹。
Ann Allergy. 1979 Nov;43(5):289-90.
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