Tanaka K, Ohtani S, Shigeno K
Poult Sci. 1983 Mar;62(3):445-51. doi: 10.3382/ps.0620445.
The effect of the increasing the energy content of the diet by supplementation with increasing amounts of carbohydrate on hepatic lipogenesis and the activities of associated enzymes of liver was examined in force-fed growing chicks. Hepatic lipogenesis and the activities of nicotinamide adenine dinucleotide phosphate (NADP-MDH)-malate dehydrogenase (EC 1.1.1.40) and citrate cleavage enzyme (EC 4.1.3.8) in liver were significantly increased as dietary metabolizable energy (ME) increased by supplementation of carbohydrate. Triglyceride content in liver significantly increased as dietary ME increased by supplementation of carbohydrate. The results demonstrated a positive correlation between hepatic fatty acid synthesis and the activities of NADP-malate dehydrogenase and citrate cleavage enzyme in liver.
通过给强制喂食的生长雏鸡补充不同量碳水化合物来增加日粮能量含量,研究其对肝脏脂肪生成及肝脏相关酶活性的影响。随着日粮中通过补充碳水化合物使代谢能(ME)增加,肝脏脂肪生成以及肝脏中烟酰胺腺嘌呤二核苷酸磷酸(NADP-MDH)-苹果酸脱氢酶(EC 1.1.1.40)和柠檬酸裂解酶(EC 4.1.3.8)的活性显著增加。随着日粮中通过补充碳水化合物使ME增加,肝脏中的甘油三酯含量显著增加。结果表明肝脏脂肪酸合成与肝脏中NADP-苹果酸脱氢酶和柠檬酸裂解酶的活性呈正相关。