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[大鼠和犬的季节性放射敏感性]

[Seasonal radiosensitivity of rats and dogs].

作者信息

Rogacheva S A, Luzanova O V, Kirillova E N, Murzina L D, Uriadnitskaia T I

出版信息

Radiobiologiia. 1983 Mar-Apr;23(2):205-9.

PMID:6844558
Abstract

The data are submitted obtained on 10.5 thousands Wistar rats and 350 mongrel dogs exposed to gamma-radiation (LD40-LD100) in different seasons. The radiosensitivity of both animal species was the highest in autumn (August and September) and the lowest in winter (February and January). The seasonal DMF for rats and dogs with LD16, LD50 and LD84 was 1.24 and 1.31, 1.13 and 1.17 and 1.04 and 1.07, respectively. The curves for seasonal radiosensitivity of dogs with LD84, LD50 and LD16, exhibited a single--phase character throughout a year. For rats, the seasonal radiosensitivity curves with LD84 were single-phase, and the curve with LD50, and particularly LD16, exhibited the second peak of radioresistance in June. The increase in radioresistance of rats and dogs correlated with the increase in number of leukocytes in the peripheral blood of animals.

摘要

这些数据是在不同季节对10500只Wistar大鼠和350只杂种狗进行γ射线辐射(LD40 - LD100)后获得的。两种动物的放射敏感性在秋季(8月和9月)最高,在冬季(1月和2月)最低。LD16、LD50和LD84的大鼠和狗的季节剂量效应系数分别为1.24和1.31、1.13和1.17、1.04和1.07。LD84、LD50和LD16的狗的季节放射敏感性曲线在全年呈现单相特征。对于大鼠,LD84的季节放射敏感性曲线是单相的,LD50尤其是LD16的曲线在6月出现第二个放射抗性峰值。大鼠和狗放射抗性的增加与动物外周血白细胞数量的增加相关。

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