Maickel R P, Tocco D R
Res Commun Chem Pathol Pharmacol. 1983 Feb;39(2):201-10.
Repetitive daily dosage (2.0 mEq/kg) of LiCl to rats maintained on a restricted fluid intake system resulted in cyclical increases and decreases in volume consumed on about a 10 day interval. At a higher dose (4.0 mEq/kg) a similar treatment led to death of the animals in 10 days. Both doses were associated with polyuria and weight loss.
对限液摄入系统饲养的大鼠每日重复给予氯化锂(2.0 毫当量/千克),导致饮水量以约 10 天的间隔呈周期性增减。给予更高剂量(4.0 毫当量/千克)并进行类似处理,会使动物在 10 天内死亡。这两种剂量均与多尿和体重减轻有关。