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CT扫描时代老年人的颅内脑膜瘤

Intracranial meningiomas in the elderly in the CT scan era.

作者信息

Papo I

出版信息

Acta Neurochir (Wien). 1983;67(3-4):195-204. doi: 10.1007/BF01401421.

Abstract

Intracranial meningiomas diagnosed and operated upon in similar five-year periods before and after CT scan are analysed. In the latter period the overall number of meningiomas and the average age of the patients have increased--tumours from 77 to 186, and average age from 50 to 56. All patients but one from the first group were operated on, while only 155 from the second group underwent surgery. Operation was rejected in 31 patients for different reasons. In the pre-CT scan epoch 25% of patients who were operated on were over 60 and 9% were over 65, whereas in the CT scan era these rates have risen to 35 and 21% respectively. Mortality and good recovery rate were the same in both groups up to 65 years of age. After 65, postoperative complications and mortality increased steeply: of the patients over 65 in whom the growth was excised 55% died. The radical surgery of intracranial meningiomas in geriatric patients over 65 still remains a tremendous challenge despite all the advances in operative technique, neuroanesthesia and intensive care. On these grounds, in such patients surgical indications should be carefully evaluated.

摘要

对在CT扫描前后相似的五年期间诊断并接受手术的颅内脑膜瘤进行了分析。在后一时期,脑膜瘤的总数和患者的平均年龄有所增加——肿瘤数量从77例增至186例,平均年龄从50岁增至56岁。第一组除1例患者外均接受了手术,而第二组只有155例患者接受了手术。31例患者因不同原因被拒绝手术。在CT扫描前的时期,接受手术的患者中有25%年龄超过60岁,9%年龄超过65岁,而在CT扫描时代,这些比例分别升至35%和21%。两组65岁以下患者的死亡率和良好恢复率相同。65岁以后,术后并发症和死亡率急剧上升:65岁以上切除肿瘤的患者中有55%死亡。尽管手术技术、神经麻醉和重症监护取得了所有进展,但65岁以上老年患者颅内脑膜瘤的根治性手术仍然是一项巨大挑战。基于这些原因,对此类患者的手术指征应仔细评估。

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