• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年(70岁以上)颅内脑膜瘤。30例手术病例的回顾性研究。

Intracranial meningiomas in the elderly (over 70 years old). A retrospective study of 30 surgical cases.

作者信息

Djindjian M, Caron J P, Athayde A A, Février M J

机构信息

Department of Neurosurgery, Hôpital Henri Mondor, Créteil, France.

出版信息

Acta Neurochir (Wien). 1988;90(3-4):121-3. doi: 10.1007/BF01560565.

DOI:10.1007/BF01560565
PMID:3354358
Abstract

The decision to operate on a patient older than 70 years for an intracranial meningioma is always difficult. Therefore a series of meningiomas treated surgically in 30 cases older than 70 years has been reconsidered and studied according to the following parameters: Karnofsky's rating scale, physiological status of the patient (A.S.A. criteria), perifocal oedema and mass effect. The locations of the meningiomas were: convexity 13, parasagittal 6, falx 2, pterion (sphenoid ridge) 5, orbito-cranial 3, jugum sphenoidale 1, tentorium (occipital) 1. Postoperative survival at day 30 shows a mortality rate of 23% which increases to 37% at day 90 including causes like decubitus ulcers and 3 cases of fatal pulmonary embolism. In a comparable series of 31 cases from 60 to 70 years, mortality rate was only 16% at day 90. Two parameters seem essential for quantifying surgical risk: clinical status, oedema and mass effect, evaluated by CT scan. The best conditions seem combined when Karnofsky rating scale is higher than or equal to 50 with no or only limited perifocal hypodensity and without mass effect. Although meningiomas may remain dormant for many years or can be kept under control medically for some time, their development is unpredictable. We think therefore that a reasonable surgical risk can be taken on patients with good physical status and favourable parameters at the time of diagnosis, particularly if the meningioma is located at the convexity where the risk of recurrence is minimal. On the other hand, patients with unfavourable parameters are not recommended for surgery.

摘要

对于70岁以上的颅内脑膜瘤患者,决定是否进行手术总是很困难。因此,我们根据以下参数重新审视并研究了30例70岁以上接受手术治疗的脑膜瘤病例:卡诺夫斯基评分量表、患者的生理状态(美国麻醉医师协会标准)、瘤周水肿和占位效应。脑膜瘤的位置分别为:凸面13例、矢状窦旁6例、大脑镰2例、翼点(蝶骨嵴)5例、眶颅3例、蝶骨平台1例、小脑幕(枕部)1例。术后30天的生存率显示死亡率为23%,到90天时升至37%,死因包括褥疮和3例致命的肺栓塞。在一个由60至70岁患者组成的31例可比系列病例中,90天时的死亡率仅为16%。有两个参数似乎对量化手术风险至关重要:通过CT扫描评估的临床状态、水肿和占位效应。当卡诺夫斯基评分量表高于或等于50,且无或仅有有限的瘤周低密度影且无占位效应时,似乎具备了最佳条件。尽管脑膜瘤可能多年保持静止状态,或者在一段时间内可以通过药物控制,但它们的发展是不可预测的。因此,我们认为对于诊断时身体状况良好且参数有利的患者,可以承担合理的手术风险,特别是如果脑膜瘤位于凸面,复发风险最小。另一方面,不建议参数不利的患者进行手术。

相似文献

1
Intracranial meningiomas in the elderly (over 70 years old). A retrospective study of 30 surgical cases.老年(70岁以上)颅内脑膜瘤。30例手术病例的回顾性研究。
Acta Neurochir (Wien). 1988;90(3-4):121-3. doi: 10.1007/BF01560565.
2
Intracranial meningiomas in elderly patients. Postoperative morbidity and mortality. Factors predictive of outcome.老年患者的颅内脑膜瘤。术后发病率和死亡率。预后的预测因素。
Acta Neurochir (Wien). 1990;102(3-4):98-102. doi: 10.1007/BF01405421.
3
Surgical treatment of parasagittal and falx meningiomas.矢状窦旁和大脑镰脑膜瘤的外科治疗
Neurol Neurochir Pol. 2007 Jul-Aug;41(4):306-14.
4
Single-fraction radiosurgery of benign intracranial meningiomas.良性颅内脑膜瘤单次分割放射外科治疗。
Neurosurgery. 2012 Sep;71(3):604-12; discussion 613. doi: 10.1227/NEU.0b013e31825ea557.
5
Analysis of the results of recurrent intracranial meningiomas treated with re-radiosurgery.复发性颅内脑膜瘤再行放射外科治疗的结果分析
Clin Neurol Neurosurg. 2017 Feb;153:93-101. doi: 10.1016/j.clineuro.2016.12.014. Epub 2016 Dec 29.
6
Resection of falx and parasagittal meningioma: complication avoidance.大脑镰旁矢状窦旁脑膜瘤切除术:并发症的避免
J Neurooncol. 2016 Nov;130(2):253-262. doi: 10.1007/s11060-016-2283-x. Epub 2016 Oct 24.
7
Surgery for intracranial meningiomas in the elderly: a clinical-radiological grading system as a predictor of outcome.老年颅内脑膜瘤手术:一种作为预后预测指标的临床-放射学分级系统
J Neurosurg. 2005 Feb;102(2):290-4. doi: 10.3171/jns.2005.102.2.0290.
8
Surgery for convexity meningiomas.凸面脑膜瘤的手术治疗。
Neurosurgery. 2008 Sep;63(3):427-33; discussion 433-4. doi: 10.1227/01.NEU.0000310692.80289.28.
9
Retrospective Analysis of 449 Intracranial Meningioma Patients Operated Between 2007 and 2013 at a Single Institute.对2007年至2013年在某单一机构接受手术的449例颅内脑膜瘤患者的回顾性分析。
Turk Neurosurg. 2018;28(1):1-6. doi: 10.5137/1019-5149.JTN.17866-16.1.
10
The further surgical experiences in intracranial meningiomas at Songklanagarind Hospital.宋卡纳加拉医院颅内脑膜瘤的进一步手术经验
J Med Assoc Thai. 1998 Feb;81(2):80-6.

引用本文的文献

1
The safety and use of perioperative dexamethasone in the perioperative management of primary sporadic supratentorial meningiomas.围手术期地塞米松在原发性散发性幕上脑膜瘤围手术期管理中的安全性及应用
Front Oncol. 2024 Apr 23;14:1379692. doi: 10.3389/fonc.2024.1379692. eCollection 2024.
2
Surgical Therapy of Non-Skull Base Meningiomas.非颅底脑膜瘤的外科治疗。
Adv Exp Med Biol. 2023;1416:79-94. doi: 10.1007/978-3-031-29750-2_7.
3
Older meningioma patients: a retrospective population-based study of risk factors for morbidity and mortality after neurosurgery.

本文引用的文献

1
Brain tumors in the elderly.老年人脑肿瘤
JAMA. 1981 Jul 3;246(1):53-5.
2
Intracranial meningiomas in the elderly in the CT scan era.CT扫描时代老年人的颅内脑膜瘤
Acta Neurochir (Wien). 1983;67(3-4):195-204. doi: 10.1007/BF01401421.
3
Morbidity, mortality, and quality of life following surgery for intracranial meningiomas. A retrospective study in 257 cases.颅内脑膜瘤手术后的发病率、死亡率及生活质量。一项对257例病例的回顾性研究。
老年脑膜瘤患者:神经外科术后发病率和死亡率的危险因素回顾性基于人群研究。
Acta Neurochir (Wien). 2022 Nov;164(11):2987-2997. doi: 10.1007/s00701-022-05336-1. Epub 2022 Aug 18.
4
Skull base versus non-skull base meningioma surgery in the elderly.老年人颅底与非颅底脑膜瘤手术比较。
Neurosurg Rev. 2019 Dec;42(4):961-972. doi: 10.1007/s10143-018-1005-6. Epub 2018 Jul 5.
5
Pathogenesis of peri-tumoral edema in intracranial meningiomas.颅内脑膜瘤瘤周水肿的发病机制。
Neurosurg Rev. 2019 Mar;42(1):59-71. doi: 10.1007/s10143-017-0897-x. Epub 2017 Aug 24.
6
Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma.老年脑膜瘤患者手术治疗的当前证据综述
Neurol Med Chir (Tokyo). 2017 Oct 15;57(10):521-533. doi: 10.2176/nmc.ra.2017-0011. Epub 2017 Aug 15.
7
Surgical Experience of Infratentorial Meningiomas : Clinical Series at a Single Institution during the 20-Year Period.幕下脑膜瘤的手术经验:单一机构20年期间的临床系列研究
J Korean Neurosurg Soc. 2014 Jun;55(6):321-30. doi: 10.3340/jkns.2014.55.6.321. Epub 2014 Jun 30.
8
Trends in intracranial meningioma surgery and outcome: a Nationwide Inpatient Sample database analysis from 2001 to 2010.颅内脑膜瘤手术及疗效趋势:2001 至 2010 年全国住院患者样本数据库分析。
J Neurooncol. 2013 Sep;114(3):299-307. doi: 10.1007/s11060-013-1183-6. Epub 2013 Jul 13.
9
Outcome comparison between younger and older patients undergoing intracranial meningioma resections.颅内脑膜瘤切除术的年轻与老年患者的结局比较。
J Neurooncol. 2013 Sep;114(2):219-27. doi: 10.1007/s11060-013-1173-8. Epub 2013 Jun 5.
10
Brain oedema in patients with intracranial meningioma. Correlation between clinical, radiological, and histological factors and the presence and intensity of oedema.颅内脑膜瘤患者的脑水肿。临床、放射学和组织学因素与水肿的存在及严重程度之间的相关性。
Acta Neurochir (Wien). 1996;138(5):485-93; discussion 493-4. doi: 10.1007/BF01411166.
J Neurosurg. 1984 Jan;60(1):52-60. doi: 10.3171/jns.1984.60.1.0052.
4
[Hypodensities accompanying various meningiomas in x-ray computed tomography].[X线计算机断层扫描中各种脑膜瘤伴随的低密度影]
Neurochirurgie. 1984;30(4):225-33.
5
The neurosurgery of old age.老年神经外科手术
Cesk Neurol. 1968 Mar;31(2):73-9.
6
Neurosurgery in the older patient.老年患者的神经外科手术。
Postgrad Med J. 1975 Jul;51(597):453-6. doi: 10.1136/pgmj.51.597.453.
7
Intracranial meningiomas: experiences at the Mayo Clinic.颅内脑膜瘤:梅奥诊所的经验
Neurol Med Chir (Tokyo). 1979 Jul;19(7):569-74. doi: 10.2176/nmc.19.569.