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西咪替丁与胃血流量

Cimetidine and gastric blood flow.

作者信息

Delaney J P, Michel H M, Bond J

出版信息

Surgery. 1978 Aug;84(2):190-3.

PMID:684610
Abstract

The influence of cimetidine on blood flow to the gastric corpus and antrum of the dog was studied using the double isotope microsphere distribution technique. This H2 receptor antagonist caused no changes in blood flow to any portion of the stomach nor did it alter systemic circulatory parameters. The therapeutic effects of cimetidine in diffuse gastric mucosal bleeding depend on some factor other than microcirculatory changes.

摘要

使用双同位素微球分布技术研究了西咪替丁对犬胃体和胃窦血流的影响。这种H2受体拮抗剂对胃的任何部分的血流均无影响,也未改变全身循环参数。西咪替丁对弥漫性胃黏膜出血的治疗作用取决于微循环变化以外的某些因素。

相似文献

1
Cimetidine and gastric blood flow.西咪替丁与胃血流量
Surgery. 1978 Aug;84(2):190-3.
2
Cimetidine prevents reduction in gastric mucosal blood flow during shock.西咪替丁可防止休克期间胃黏膜血流减少。
Surgery. 1978 Jul;84(1):113-9.
3
The significance of gastric mucosal blood flow and acid secretion in erosive gastritis following hemorrhagic shock in cats.猫失血性休克后糜烂性胃炎中胃黏膜血流和胃酸分泌的意义。
Acta Chir Scand. 1982;148(2):113-9.
4
[The parasympathetic nervous system and regulation of blood flow in the gastric mucosa in albino rats and dogs].[白化大鼠和狗的副交感神经系统与胃黏膜血流调节]
Fiziol Zh SSSR Im I M Sechenova. 1984 Apr;70(4):472-7.
5
[The effect of cimetidine to suppress the reduction of gastric mucosal blood flow caused by immobilization in water--its relationship to noradrenaline].西咪替丁对抑制因水浸制动引起的胃黏膜血流量减少的作用——及其与去甲肾上腺素的关系
Nihon Geka Gakkai Zasshi. 1989 Dec;90(12):1959-64.
6
The influence of cimetidine, a histamine H2-receptor antagonist, on the gastric effects of reserpine in rats.组胺H2受体拮抗剂西咪替丁对利血平在大鼠体内胃效应的影响。
Eur J Pharmacol. 1981 Mar 12;70(2):139-48. doi: 10.1016/0014-2999(81)90208-9.
7
[Neutral-red clearance technique for measuring gastric mucosal blood flow in the rat (author's transl)].[用中性红清除技术测量大鼠胃粘膜血流量(作者译)]
Arzneimittelforschung. 1981;31(4):675-7.
8
Effect of cimetidine on canine gastric mucosal pH and blood flow.西咪替丁对犬胃黏膜pH值和血流量的影响。
Am J Surg. 1983 Jan;145(1):24-9. doi: 10.1016/0002-9610(83)90161-7.
9
Effects of hemorrhagic shock on gastric blood flow and acid secretion in cats.失血性休克对猫胃血流量及胃酸分泌的影响。
Acta Chir Scand. 1981;147(2):81-8.
10
Effect of cimetidine on augmented gastric blood flow in duodenal ulcer patients.西咪替丁对十二指肠溃疡患者胃血流量增加的影响。
Gut. 1984 Oct;25(10):1093-9. doi: 10.1136/gut.25.10.1093.

引用本文的文献

1
Does gastric aminopyrine clearance reflect gastric mucosal blood flow or parietal cell function?胃氨基比林清除率反映胃黏膜血流还是壁细胞功能?
Gut. 1981 Dec;22(12):997-1002. doi: 10.1136/gut.22.12.997.
2
[Control of gastric acidity with cimetidine given as premedication before general anesthesia: efficacy and tolerance].[在全身麻醉前使用西咪替丁进行预处理控制胃酸分泌:疗效与耐受性]
Can Anaesth Soc J. 1981 Sep;28(5):442-9. doi: 10.1007/BF03010353.
3
Effect of cimetidine on augmented gastric blood flow in duodenal ulcer patients.西咪替丁对十二指肠溃疡患者胃血流量增加的影响。
Gut. 1984 Oct;25(10):1093-9. doi: 10.1136/gut.25.10.1093.
4
Stimulation of gastric acid secretion increases mucosal blood flow in immediate vicinity of parietal cells in baboons.刺激胃酸分泌会增加狒狒壁细胞紧邻区域的黏膜血流量。
Dig Dis Sci. 1988 May;33(5):545-51. doi: 10.1007/BF01798355.
5
Histamine H2-receptor antagonists versus prostaglandins in the treatment of peptic ulcer disease.组胺H2受体拮抗剂与前列腺素在消化性溃疡疾病治疗中的比较
Drugs. 1989 Apr;37(4):391-401. doi: 10.2165/00003495-198937040-00001.