Mirowski M, Reid P R, Winkle R A, Mower M M, Watkins L, Stinson E B, Griffith L S, Kallman C H, Weisfeldt M L
Ann Intern Med. 1983 May;98(5 Pt 1):585-8. doi: 10.7326/0003-4819-98-5-585.
Fifty-two patients who survived several arrhythmic cardiac arrests had implantation of an automatic defibrillator along with additional cardiovascular surgery as indicated. The mean follow-up was 14.4 months and the longest was 3 years. In the hospital, the implanted devices identified and reverted 82 episodes of spontaneous and 81 of 99 episodes of induced malignant tachyarrhythmias. There were 62 automatic resuscitations in 17 patients outside the hospital. Twelve patients died; four of the deaths were not witnessed. These deaths represent a 22.9% total and 8.5% sudden-death 1-year mortality rate. Because the expected 1-year mortality in patients without the automatic defibrillator was calculated to be 48%, there was an estimated 52% decrease in anticipated total deaths. The automatic implantable defibrillator can identify and correct potentially lethal ventricular tachyarrhythmias, leading to a substantial increase in 1-year survival in properly selected high-risk patients.
52名经历过多次心律失常性心脏骤停且存活下来的患者，根据需要植入了自动除颤器并接受了额外的心血管手术。平均随访时间为14.4个月，最长为3年。在医院里，植入装置识别并逆转了82次自发性恶性快速心律失常发作以及99次诱发性恶性快速心律失常发作中的81次。在院外，17名患者发生了62次自动复苏。12名患者死亡；其中4例死亡未被目击。这些死亡占总死亡率的22.9%，1年猝死死亡率为8.5%。由于计算得出未使用自动除颤器的患者预期1年死亡率为48%，因此预计总死亡人数减少了52%。自动植入式除颤器能够识别并纠正潜在致命的室性快速心律失常，从而使经过恰当选择的高危患者1年生存率大幅提高。
