金刚烷胺与利巴韦林对流感病毒的体外比较活性：可能的临床意义。
Comparative activity of amantadine and ribavirin against influenza virus in vitro: possible clinical relevance.
作者信息
Browne M J, Moss M Y, Boyd M R
出版信息
Antimicrob Agents Chemother. 1983 Mar;23(3):503-5. doi: 10.1128/AAC.23.3.503.
Abstract
The activities of amantadine and ribavirin against influenza A viruses were compared against low-multiplicity (plaque inhibition) and high-multiplicity (protein synthesis inhibition) infections. Our results suggest that the predictive value of in vitro data for the clinic may be improved by consideration of tests against a high-multiplicity infection.
摘要
比较了金刚烷胺和利巴韦林对甲型流感病毒在低 multiplicity（蚀斑抑制）和高 multiplicity（蛋白质合成抑制）感染情况下的活性。我们的结果表明，通过考虑针对高 multiplicity 感染的测试，体外数据对临床的预测价值可能会得到提高。
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