Heinicke M H, Zarrabi M H, Gorevic P D
Ann Rheum Dis. 1983 Apr;42(2):196-200. doi: 10.1136/ard.42.2.196.
A 60-year-old man presented with polyarthralgias, a psoriasiform rash, and severe elbow pain. Peripheral blood smear and bone marrow biopsy established a diagnosis of myelofibrosis with myeloid metaplasia. Biopsy of the skin lesions revealed a nonspecific dermatitis. The clinical presentation was inconsistent with psoriatic arthritis, and there was no evidence for associated gout or collagen-vascular disease. Histological examination of tissue taken at the time of synovectomy indicated elbow arthritis to be due to myeloid metaplasia involving the synovial membrane.
一名60岁男性出现多关节痛、银屑病样皮疹和严重的肘部疼痛。外周血涂片和骨髓活检确诊为骨髓纤维化伴髓外化生。皮肤病变活检显示为非特异性皮炎。临床表现与银屑病关节炎不符，也没有证据表明存在相关的痛风或胶原血管病。滑膜切除术时所取组织的组织学检查表明，肘部关节炎是由于髓外化生累及滑膜所致。
