Furman J M, Perlman S, Baloh R W
Arch Neurol. 1983 Jun;40(6):343-6. doi: 10.1001/archneur.1983.04050060043006.
Twenty-four patients with well-documented Friedreich's ataxia underwent quantitative oculomotor testing. A consistent pattern of eye movement abnormalities was observed. This pattern included fixation instability, inaccurate saccades with normal peak velocity, impaired smooth pursuit and optokinetic slow phases, decreased vestibulo-ocular reflex gain, and impaired visual-vestibular interaction. This pattern corresponds to the known pathologic changes of Friedreich's ataxia and can be useful in the differential diagnosis of cerebellar atrophy.
24例有充分记录的弗里德赖希共济失调患者接受了定量动眼神经测试。观察到一致的眼球运动异常模式。这种模式包括注视不稳定、峰值速度正常但扫视不准确、平稳跟踪和视动性慢相受损、前庭眼反射增益降低以及视前庭相互作用受损。这种模式与弗里德赖希共济失调已知的病理变化相符，可用于小脑萎缩的鉴别诊断。
