Ravich W J, Bayless T M, Thomas M
Gastroenterology. 1983 Jan;84(1):26-9.
Fructose is an increasingly important commercial sweetener. However, some patients report abdominal symptoms after ingesting fructose-containing foods. The completeness of fructose absorption by the small intestine was assessed by breath hydrogen analysis in 16 healthy volunteers and incomplete absorption was defined as a peak rise in breath hydrogen of greater than 20 parts per million. Fructose, 50 g as a 10% solution, was incompletely absorbed in 6 of 16 subjects (37.5%). Incomplete absorption was associated with symptoms of cramps or diarrhea, or both in 5 of these 6 individuals. Incomplete absorption was both concentration- and dose-related. Three subjects incompletely absorbed 37.5 g of fructose. In comparison, all 15 subjects who were studied after ingestion of sucrose, 50 g and a 10% solution, completely absorbed this sugar load. Incomplete absorption of fructose should be considered as a possible case of gastrointestinal symptoms.
果糖是一种越来越重要的商业甜味剂。然而，一些患者在摄入含果糖食物后会出现腹部症状。通过对16名健康志愿者进行呼气氢分析来评估小肠对果糖的吸收完整性，呼气氢峰值上升超过百万分之20被定义为吸收不完全。16名受试者中有6名（37.5%）对50克10%溶液的果糖吸收不完全。这6名个体中有5名吸收不完全与痉挛或腹泻症状或两者都有关。吸收不完全与浓度和剂量相关。三名受试者对37.5克果糖吸收不完全。相比之下，所有15名摄入50克10%溶液蔗糖后接受研究的受试者都完全吸收了这种糖负荷。果糖吸收不完全应被视为胃肠道症状的一种可能情况。
