Sandler R S, Sandler D P
Gastroenterology. 1983 Jan;84(1):51-7.
Individuals who have received pelvic irradiation are reported to be at increased risk to develop subsequent malignancies in the large bowel. In order to plan appropriate follow-up for these patients, it is necessary to understand the magnitude of their risk. In this paper we review the literature on colorectal cancer after irradiation and estimate the excess risk based upon available data. Women who are irradiated for gynecologic cancer may have a relative risk for subsequent colorectal cancer of 2.0-3.6 based on best estimates. This risk is calculated independent of any risk imposed by underlying disease. These women are appropriate targets for careful surveillance for colorectal cancer.
据报道，接受盆腔放疗的个体患后续大肠恶性肿瘤的风险会增加。为了为这些患者制定适当的随访计划，有必要了解其风险程度。在本文中，我们回顾了关于放疗后结直肠癌的文献，并根据现有数据估计额外风险。根据最佳估计，因妇科癌症接受放疗的女性患后续结直肠癌的相对风险可能为2.0至3.6。该风险是独立于潜在疾病所带来的任何风险计算得出的。这些女性是结直肠癌仔细监测的合适对象。
