Smith E J, Ninin D T, Keays A C
S Afr Med J. 1983 Jan 15;63(3):88-90.
A report of a case of idiopathic chondrolysis of the right hip in a 13-year-old Black girl is presented. Radiographs and microbiological and biochemical investigations excluded all other diseases. Cartilage and synovium were removed at biopsy of the right hip. Macroscopic and histopathological studies showed the typical features of idiopathic chondrolysis. Transmission electron microscopy confirmed the histological findings. Scanning electron microscopy highlighted the irregular pitted and fibrillated surface of the cartilage. Immunofluorescent studies on cartilage and synovium were negative. The possible pathogenesis of the disease is discussed, but the cause still remains unknown.
本文报告了一名13岁黑人女孩右髋特发性软骨溶解症的病例。X线片、微生物学及生化检查排除了所有其他疾病。右髋活检时切除了软骨和滑膜。大体及组织病理学研究显示了特发性软骨溶解症的典型特征。透射电子显微镜证实了组织学检查结果。扫描电子显微镜突出显示了软骨表面不规则的凹坑和纤维状。软骨和滑膜的免疫荧光研究结果为阴性。文中讨论了该病可能的发病机制,但病因仍不明。