West M R, Kenicer K J, Faed M J
Br J Dermatol. 1983 May;108(5):533-40. doi: 10.1111/j.1365-2133.1983.tb01053.x.
The growth of epidermal cells derived from clinically normal skin of psoriatic patients and controls has been studied in culture. Growth rates were measured in secondary cultures established with 5 x 10(4) cells/35 mm plate without feeder layers by determining the plating efficiency, and cell yield and surface area of growth at the end of a 14-day culture period. There was no significant correlation of plating efficiency, cell yield/colony or surface area/colony with the sex or age of the donor in either the normal or psoriatic groups. The morphological development of normal and psoriatic epidermal cell cultures was similar. Comparisons of plating efficiency, cell yield/colony and surface area/colony for the normal and psoriatic groups revealed no significant difference.
对银屑病患者和对照组临床正常皮肤来源的表皮细胞在培养中的生长情况进行了研究。通过测定接种效率，并在14天培养期结束时测定细胞产量和生长的表面积，在无饲养层的情况下，以5×10⁴个细胞/35毫米培养皿建立传代培养物，来测量生长速率。在正常组和银屑病组中，接种效率、细胞产量/集落或表面积/集落与供体的性别或年龄均无显著相关性。正常和银屑病表皮细胞培养物的形态发育相似。正常组和银屑病组在接种效率、细胞产量/集落和表面积/集落方面的比较显示无显著差异。
