Holje L, Hildebrand C, Fried K
Brain Res. 1983 Apr 25;266(1):133-6. doi: 10.1016/0006-8993(83)91315-x.
Neonatal rats were given capsaicin subcutaneously. Controls received vehicle only. Six months later the nerve fiber populations in the dorsal root L4, in the inferior alveolar nerve and in mandibular molar pulps were examined by electron microscopy. The proportion of unmyelinated axons was found to be markedly decreased in root and nerve specimens from capsaicin-treated rats. However, the pulpal nerves in tooth specimens from these rats showed no obvious alterations.
给新生大鼠皮下注射辣椒素。对照组仅给予赋形剂。6个月后，通过电子显微镜检查L4背根、下牙槽神经和下颌磨牙牙髓中的神经纤维群。发现辣椒素处理组大鼠的神经根和神经标本中无髓鞘轴突的比例明显降低。然而，这些大鼠牙齿标本中的牙髓神经未显示出明显变化。
