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新生儿辣椒素不影响自主神经系统的无髓传出纤维:功能证据。

Neonatal capsaicin does not affect unmyelinated efferent fibers of the autonomic nervous system: functional evidence.

作者信息

Cervero F, McRitchie H A

出版信息

Brain Res. 1982 May 6;239(1):283-8. doi: 10.1016/0006-8993(82)90853-8.

Abstract

Visceral nociceptive thresholds, viscero-visceral reflexes and the effects of efferent stimulation of autonomic nerves has been studied in adult rats treated at birth with capsaicin. These animals showed visceral analgesia and depressed visceral reflexes. However, stimulation of unmyelinated efferent fibers in autonomic nerves produced normal effects. It is concluded that neonatal treatment with capsaicin destroys selectively unmyelinated afferent fibers.

摘要

在出生时用辣椒素处理的成年大鼠中,研究了内脏伤害性感受阈值、内脏-内脏反射以及自主神经传出刺激的影响。这些动物表现出内脏镇痛和内脏反射抑制。然而,自主神经中无髓鞘传出纤维的刺激产生正常效应。得出的结论是,新生儿期用辣椒素处理会选择性地破坏无髓鞘传入纤维。

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