Chaudhry A P, Cutler L S, Satchidanand S, Labay G, Raj M S, Lin C C
Cancer. 1983 Jul 1;52(1):105-11. doi: 10.1002/1097-0142(19830701)52:1<105::aid-cncr2820520120>3.0.co;2-b.
A detailed electronmicroscopic study on glycogen-rich tumor is presented. The neoplasm originated from the minor salivary glands on the ventral surface of the tongue. The role of myoepithelial cells in the histogenesis of this lesion is not supported. It is proposed that the tumor arises from "undifferentiated" stem cells analogous to cells in the "end bud" stage of salivary gland morphogenesis. The presence of a large amount of glycogen is secondary to defective carbohydrate metabolism within the tumor cells.
本文呈现了一项关于富含糖原肿瘤的详细电子显微镜研究。该肿瘤起源于舌腹面的小唾液腺。肌上皮细胞在该病变组织发生中的作用未得到证实。有人提出，该肿瘤起源于类似于唾液腺形态发生“终末芽”阶段细胞的“未分化”干细胞。肿瘤细胞内大量糖原的存在是碳水化合物代谢缺陷的继发结果。
