Manzoni G C, Terzano M G, Bono G, Micieli G, Martucci N, Nappi G
Cephalalgia. 1983 Mar;3(1):21-30. doi: 10.1046/j.1468-2982.1983.0301021.x.
Anamnestic data and clinical features were accurately investigated in 180 patients with cluster headache; 161 were episodic sufferers and 19 were chronic. A significantly high familial incidence of coronary heart disease was found. The patients' medical history revealed a significantly high incidence of peptic ulcer disease and head injury with brain concussion. It is stressed that the side on which head injury took place is very frequently the same side on which cluster headache is located, although the latency between the two events appears to be a long one. The study of timing of cluster periods suggests, for some patients, a constant, typical temporal pattern not necessarily related to seasons or the months of of the year. Cluster attacks frequently occur during certain periods of the day (onset being most frequent between 1 and 3 p.m.). Cluster headache cannot be considered as a nocturnal headache.
对180例丛集性头痛患者的既往病史数据和临床特征进行了准确调查；其中161例为发作性患者，19例为慢性患者。发现冠心病的家族发病率显著较高。患者的病史显示消化性溃疡疾病和脑震荡头部损伤的发病率显著较高。需要强调的是，头部受伤的一侧非常频繁地与丛集性头痛所在的一侧相同，尽管这两个事件之间的潜伏期似乎很长。对丛集期时间的研究表明，对一些患者来说，存在一种固定的、典型的时间模式，不一定与季节或一年中的月份相关。丛集性发作经常发生在一天中的特定时间段（最常发作时间为下午1点至3点之间）。丛集性头痛不能被视为夜间头痛。
