Kincaid-Smith P, Bennett W M, Dowling J P, Ryan G B
Clin Nephrol. 1983 Apr;19(4):206-10.
A 16 year old male with a history of recurrent synpharyngitic macroscopic hematuria presented with severe loin pain, macroscopic hematuria and oliguric acute renal failure. Although renal biopsy showed mesangial IgA nephropathy with focal and segmental proliferation with crescents, the extent of glomerular involvement could not explain the severe functional disturbance. Intratubular obstruction and tubular necrosis secondary to the presence of severe glomerular bleeding provide a better explanation. Although renal failure resolved spontaneously, the long-term effects of episodes of this type on structure and function is unknown.
一名16岁男性，有复发性咽峡炎后肉眼血尿病史，此次出现严重的腰痛、肉眼血尿和少尿性急性肾衰竭。尽管肾活检显示为系膜IgA肾病，伴有局灶节段性增生及新月体形成，但肾小球受累程度无法解释严重的功能障碍。严重肾小球出血继发肾小管内梗阻和肾小管坏死或许能更好地解释这一情况。虽然肾衰竭自行缓解，但此类发作对结构和功能的长期影响尚不清楚。
