Southam L, Pedrón N, Ponce-Monter H, Girón H, Estrada A, Lozoya X, Enríquez R G, Bejar E, Gallegos A J
Contraception. 1983 Mar;27(3):255-65. doi: 10.1016/0010-7824(83)90004-5.
The zoapatle aqueous crude extract has been used in Mexico for the last 5 centuries for the induction of labor, treatment of post-partum bleeding problems, and as a menses inducer. Today, it is sold in street markets, and its long documented history of use by humans could be taken as indirect evidence of a lack of toxicity. Rigorous pharmacological and clinical studies described here, fully confirm the empirical observations.
在过去的五个世纪里,墨西哥一直使用佐阿帕特利水粗提物来引产、治疗产后出血问题以及作为月经诱导剂。如今,它在街头市场上有售卖,其长期有记载的人类使用历史可被视为缺乏毒性的间接证据。本文所述的严格药理学和临床研究充分证实了这些经验观察结果。