Berkhoff M, Wacha H, Becker H, Ungeheuer E, Cloos O
Chirurg. 1983 Feb;54(2):94-7.
Review of 190 cases of thyroid carcinoma between 1974 and 1981 showed an increasing rate of small papillary carcinoma. The study included 46 tumors which did not exceed 15 mm in diameter. Most of these lesions (3/4) were discovered incidentally at thyroid operations of various types. In spite of the early stage of carcinoma 6 tumors were already associated with cervical nodal metastasis, cases showed multiple lesions within the thyroid gland, homolateral and bilateral. With respect to these cases total thyroidectomy and subsequent radium therapy are generally suggested.
对1974年至1981年间190例甲状腺癌病例的回顾显示，小乳头状癌的发病率呈上升趋势。该研究包括46个直径不超过15毫米的肿瘤。这些病变中的大多数（3/4）是在各种类型的甲状腺手术中偶然发现的。尽管处于癌症早期，但6个肿瘤已经伴有颈部淋巴结转移，病例显示甲状腺腺体内有多个病变，同侧和双侧均有。对于这些病例，一般建议进行全甲状腺切除术及后续镭疗。
