Chesnokova N P
Vopr Med Khim. 1978 Jul-Aug;24(4):505-10.
Demedullation of adrenal glands caused a decrease in excretion of adrenaline and vanilyl mandelic acid with simultaneous increase of adrenaline content in various rat tissues. Predemedullation of adrenal glands prevented distinctly the alterations in catecholamine metabolism, which developed in botulinic and tetanic neurointoxications. The data obtained suggest that activation of adrenergic processes is of importance in genesis of the alterations observed in catecholamine metabolism under conditions of botulinic and tetanic intoxications.
肾上腺去髓质作用导致肾上腺素和香草扁桃酸排泄减少，同时大鼠各种组织中的肾上腺素含量增加。预先进行肾上腺去髓质作用可明显防止在肉毒中毒和破伤风神经中毒时出现的儿茶酚胺代谢改变。所获得的数据表明，在肉毒中毒和破伤风中毒情况下，肾上腺素能过程的激活在儿茶酚胺代谢改变的发生中起重要作用。
