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[血液、血小板及多种组织中前列腺素的提取、分离与定量测定]

[Extraction, separation and quantitative determination of prostaglandins in blood, thrombocytes and several tissues].

作者信息

Zykova V P, Bochkareva E V, Vladimirov S S, Beliaeva T E

出版信息

Vopr Med Khim. 1978 Jul-Aug;24(4):514-9.

PMID:685196
Abstract

Modified methods, using selective organic extraction and absorption-distributional column chromatography, are described for isolation of prostglandines with high yield; the substances were differentiated by means of the methods used into series A, E, F. Use of radioimmunologic method enabled to obtain data on content of prostglandines in blood plasma and in thrombocytes of healthy people and of patients with ischemic heart impairments as well as on content of these substances in rabbit blood plasma, fatty and livery tissues.

摘要

描述了使用选择性有机萃取和吸附-分配柱色谱法的改良方法,用于高产率地分离前列腺素;通过所使用的方法将这些物质分为A、E、F系列。放射免疫法的使用能够获得健康人和缺血性心脏病患者血浆和血小板中前列腺素含量的数据,以及这些物质在兔血浆、脂肪组织和肝脏组织中的含量数据。

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