Verrillo A, de Teresa A, Nunziata G, Rucco E
Diabete Metab. 1983 Mar;9(1):9-13.
To evaluate the prevalence of diabetes in a rural community, 589 subjects in Laurino, Southern Italy, were submitted to a 50 g oral glucose tolerance test. Two hours later, blood glucose levels revealed 453 normal subjects, 36 diabetics and 100 borderline subjects. The borderline subjects were re-examined with 75 g OGTT and, according to criteria recommended by the National Diabetes Data Groups (NDDG), 29 subjects were found normal, 35 with impaired glucose tolerance (IGT) and 36 with diabetes. Final figures showed 72 diabetics (12.2%) and 35 IGT cases (5.9%). Obesity appeared strongly related to diabetes (p less than 0.05 in males and p less than 0.01 in females 40 years old and over). Diabetes was more prevalent in subjects with a positive family history (p less than 0.01). No significant difference in number was observed between male and female diabetics, nor between big babies delivered by normal women and big babies by diabetic women. The high diabetes prevalence might be partly explained by the changes created by an industrially-established dietetic influence on the rural communities in Southern Italy.
为评估一个农村社区的糖尿病患病率，意大利南部劳里诺的589名受试者接受了50克口服葡萄糖耐量试验。两小时后，血糖水平显示有453名正常受试者、36名糖尿病患者和100名临界受试者。对临界受试者进行了75克口服葡萄糖耐量试验（OGTT）复查，根据美国国家糖尿病数据组（NDDG）推荐的标准，发现29名受试者正常，35名糖耐量受损（IGT），36名患有糖尿病。最终数据显示有72名糖尿病患者（12.2%）和35例IGT病例（5.9%）。肥胖似乎与糖尿病密切相关（40岁及以上男性p<0.05，女性p<0.01）。糖尿病在有家族病史的受试者中更为普遍（p<0.01）。男性和女性糖尿病患者的数量没有显著差异，正常女性分娩的巨大儿和糖尿病女性分娩的巨大儿数量也没有显著差异。糖尿病的高患病率可能部分归因于工业化带来的饮食影响给意大利南部农村社区造成的变化。
