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苏丹北部达纳格拉社区糖尿病和糖耐量受损的高患病率。

A high prevalence of diabetes mellitus and impaired glucose tolerance in the Danagla community in northern Sudan.

作者信息

Elbagir M N, Eltom M A, Elmahadi E M, Kadam I M, Berne C

机构信息

Department of Internal Medicine, University Hospital, Uppsala, Sweden.

出版信息

Diabet Med. 1998 Feb;15(2):164-9. doi: 10.1002/(SICI)1096-9136(199802)15:2<164::AID-DIA536>3.0.CO;2-A.

Abstract

The prevalence and associated factors of diabetes mellitus (DM) and impaired glucose tolerance (IGT) were studied in a tribal community with an apparently high diabetes prevalence. A sample of 724 subjects aged > or = 25 years was selected using a multi-stage cluster method and underwent a 75 g oral glucose tolerance test. The crude prevalence of DM and IGT were 8.3% (men 9.9%; women 7.5%) and 7.9% (men 4.1%; women 9.7%), respectively. Age-adjusted prevalence rates, according to the standard population of Segi, were 10.4% (95% CI 7.7-13.2) and 9.8% (95% CI 7.2-12.5) for DM and IGT, respectively. No urban/rural differences were found in the prevalence rates of DM and IGT. New cases (5.1%) were almost twice as common as previously known cases (3.2%). Family history of diabetes, obesity, and advanced age were associated with higher rates of diabetes. The results confirmed that diabetes is common in the Danagla community compared to other communities of northern Sudan. Varying environmental, nutritional, and genetic factors may contribute to this high prevalence. These findings will have profound impact on the health services for this community and the Sudan as a whole.

摘要

在一个糖尿病患病率明显较高的部落社区,对糖尿病(DM)和糖耐量受损(IGT)的患病率及相关因素进行了研究。采用多阶段整群抽样方法选取了724名年龄≥25岁的受试者,并进行了75克口服葡萄糖耐量试验。DM和IGT的粗患病率分别为8.3%(男性9.9%;女性7.5%)和7.9%(男性4.1%;女性9.7%)。根据Segi标准人群进行年龄调整后的患病率,DM和IGT分别为10.4%(95%可信区间7.7 - 13.2)和9.8%(95%可信区间7.2 - 12.5)。DM和IGT的患病率未发现城乡差异。新发病例(5.1%)几乎是既往已知病例(3.2%)的两倍。糖尿病家族史、肥胖和高龄与糖尿病的较高发病率相关。结果证实,与苏丹北部的其他社区相比,糖尿病在达纳格拉社区很常见。不同的环境、营养和遗传因素可能导致了这种高患病率。这些发现将对该社区乃至整个苏丹的卫生服务产生深远影响。

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