Borg T K, Johnson L D, Lill P H
Dev Biol. 1983 Jun;97(2):417-23. doi: 10.1016/0012-1606(83)90098-2.
The formation and attachment of collagen to the sarcolemma of cardiac myocytes were examined in vivo in neonatal rats and hamsters and in vitro in cultures of neonatal rat myocytes. Scanning, transmission, and high-voltage electron microscopy were used to show that the collagen struts attach to specific sites on the sarcolemma just lateral to the Z band of neonatal animals. In vitro, collagen preferentially attaches to distal end of myocytes at a site where internal stress fibers also attach to the sarcolemma. Formation of the collagen struts appeared to be a multistep process involving several components of the extracellular matrix. The role of the collagen struts is involved in the distribution of force generated by muscle contraction.
在新生大鼠和仓鼠体内以及新生大鼠心肌细胞培养物中，对胶原蛋白在心肌细胞肌膜上的形成和附着情况进行了研究。利用扫描电子显微镜、透射电子显微镜和高压电子显微镜显示，胶原蛋白支柱附着于新生动物Z带外侧肌膜上的特定部位。在体外，胶原蛋白优先附着于心肌细胞的远端，此处内部应力纤维也附着于肌膜。胶原蛋白支柱的形成似乎是一个涉及细胞外基质多个成分的多步骤过程。胶原蛋白支柱的作用涉及肌肉收缩产生的力的分布。
