Borg T K, Sullivan T, Ivy J
Scan Electron Microsc. 1982(Pt 4):1775-84.
The presence and arrangement of connective tissue associated with cardiac and skeletal muscle and composed principally of collagen is clearly demonstrable by scanning and high voltage electron microscopy. The basic organization consists of a perimysium composed of bundles of collagen fibers that connect the epimysium to the endomysium. The endomysium has at least 4 components: (1) a dense weave network that surrounds myocytes, (2) myocyte-myocyte collagen struts that connect adjacent myocytes, (3) myocyte-capillary struts that connect capillaries and myocytes, and (4) a complex of single collagen fibers, glycoproteins, and glycosaminoglycans. The amount of collagen in each component varies with the function of the muscle. Different types of skeletal muscles contain different amounts of collagen depending upon the function and composition of the particular muscle. In cardiac muscle the amount of collagen varies with different species. Different regions of the heart show differences in the amount of collagen due to different functional requirements of those regions. Thus, the amount of collagen in atria is different than in the ventricles due to differences in pressure and volume of these components of the heart.
通过扫描电子显微镜和高压电子显微镜可以清楚地显示与心肌和骨骼肌相关的、主要由胶原蛋白组成的结缔组织的存在和排列。其基本组织结构包括一层肌束膜，它由胶原纤维束组成，将肌外膜与肌内膜连接起来。肌内膜至少有4个组成部分：（1）围绕肌细胞的致密编织网络；（2）连接相邻肌细胞的肌细胞-肌细胞胶原支柱；（3）连接毛细血管和肌细胞的肌细胞-毛细血管支柱；（4）由单一胶原纤维、糖蛋白和糖胺聚糖组成的复合物。每个组成部分中胶原蛋白的含量随肌肉功能而变化。不同类型的骨骼肌根据特定肌肉的功能和组成含有不同量的胶原蛋白。在心肌中，胶原蛋白的含量因物种而异。由于心脏不同区域的功能需求不同，心脏的不同区域显示出胶原蛋白含量的差异。因此，由于心脏这些组成部分的压力和容积不同，心房中的胶原蛋白含量与心室中的不同。
