Leclerc M, Luquet G
Immunol Lett. 1983 Feb;6(2):107-8. doi: 10.1016/0165-2478(83)90090-1.
In vivo inoculation of heat-killed bacteria in the coelomic cavity of starfish induces an increase of spontaneous cytotoxicity developed by axial organ (an ancestral lymphoid organ) cells, phenomenon demonstrated by an in vitro [51Cr]-release assay. This observation corroborates the existence of a sophisticated immune system in the echinoderms, a first-rate model for phylogenic study of the immune response.
在海星体腔中接种热灭活细菌会导致轴器官（一种原始淋巴器官）细胞产生的自发细胞毒性增加，这一现象通过体外[51Cr]释放试验得以证明。该观察结果证实了棘皮动物中存在复杂的免疫系统，棘皮动物是免疫反应系统发育研究的一流模型。
