Kleinberg-Zissin R, Avigad S, Yahav J, Jonas A
Isr J Med Sci. 1983 Apr;19(4):319-24.
Oral triglyceride (TG) loading tests were performed in 31 patients with gluten-sensitive enteropathy (GSE) upon gluten challenge, and the results were compared with the mucosal histology. Of 19 prechallenge tests, 16 were in the normal range previously established in this laboratory (2-h postcibal plasma TG rise greater than or equal to 55 mg/dl) although values were lower (76 +/- 38 mg/dl, mean +/- SD) than those of healthy age-matched controls (116 +/- 34 mg/dl). Postchallenge tests performed in 29 patients (both symptomatic and asymptomatic) were all pathologic (postcibal TG rise 9 +/- 18 mg/dl). Three tests performed in two patients in whom GSE was ultimately not confirmed remained normal (postcibal TG rise 82 +/- 21 mg/dl) during a 24-mo follow-up. A significant correlation was demonstrated between the TG loading test and the mucosal pathology. The test is useful in the follow-up of patients of gluten challenge and in directing the postchallenge biopsy.
对31例麸质激发试验后的麸质敏感性肠病（GSE）患者进行了口服甘油三酯（TG）负荷试验，并将结果与黏膜组织学进行了比较。在19次激发前试验中，16次处于本实验室先前确定的正常范围内（餐后2小时血浆TG升高大于或等于55mg/dl），尽管数值（76±38mg/dl，平均值±标准差）低于年龄匹配的健康对照者（116±34mg/dl）。对29例患者（有症状和无症状）进行的激发后试验均为病理性（餐后TG升高9±18mg/dl）。在两名最终未确诊为GSE的患者中进行的三次试验在24个月的随访期间保持正常（餐后TG升高82±21mg/dl）。TG负荷试验与黏膜病理学之间存在显著相关性。该试验在麸质激发试验患者的随访以及指导激发后活检方面很有用。
