[Arterial and venous blood-pressure in the mesenteric circulation of rabbits with combined infusion of secretin and norepinephrine (author's transl)].

Norepinephrine and secretin were infused into V. cava inf. and Art. mesent. sup. with a short intervall and after that immediately successive on rabbits, anesthetized by urethane-chloralose; simultaneously blood-pressure was measured in Aorta abdom., Art. mesent. sup. and V. mesent. sup. Secretin alone does not change blood-pressure; infusion of norepinephrine into V. cava inf. leads to a rise of blood-pressure of about 16% in Aorta abdom., of about 12% in Art. mesent. sup.; in V. mesent. sup. blood-pressure remained unchanged. Although secretin and norepinephrine have a contrary effect on the vascular tonus with cats, in rabbits combined infusion of secretin and norepinephrine caused an increase of blood-pressure not fewer than infusion of norepinephrine alone. Possible haemodynamic mechanisms were discussed.