嗜碱假单胞菌中儿茶酚间位裂解途径的调控
Control of catechol meta-cleavage pathway in Alcaligenes eutrophus.
作者信息
Hughes E J, Bayly R C
出版信息
J Bacteriol. 1983 Jun;154(3):1363-70. doi: 10.1128/jb.154.3.1363-1370.1983.
Abstract
Alcaligenes eutrophus 335 (ATCC 17697) metabolizes phenol and p-cresol via a catechol meta-cleavage pathway. Studies with mutant strains, each defective in an enzyme of the pathway, showed that the six enzymes assayed are induced by the primary substrate. Studies with a putative polarity mutant defective in the expression of aldehyde dehydrogenase suggested that the structural genes encoding this and subsequent enzymes of the pathway exist in the same operon. From studies with mutant strains that constitutively synthesize catechol 2,3-oxygenase and subsequent enzymes and from the coordination of repression of these enzymes by p-toluate, benzoate, and acetate, it is proposed the catechol 2,3-oxygenase structural gene is situated in this operon (2,3-oxygenase operon). Studies with regulatory mutant strains suggest that the 2,3-oxygenase operon is under negative control.
摘要
嗜碱假单胞菌335（ATCC 17697）通过儿茶酚间位裂解途径代谢苯酚和对甲酚。对该途径中每种酶有缺陷的突变菌株的研究表明，所检测的六种酶是由主要底物诱导的。对醛脱氢酶表达有缺陷的假定极性突变体的研究表明，编码该酶及该途径后续酶的结构基因存在于同一个操纵子中。通过对组成型合成儿茶酚2,3-双加氧酶及后续酶的突变菌株的研究，以及对这些酶受对甲苯酸盐、苯甲酸盐和乙酸盐阻遏的协调性研究，推测儿茶酚2,3-双加氧酶结构基因位于这个操纵子（2,3-双加氧酶操纵子）中。对调节突变菌株的研究表明，2,3-双加氧酶操纵子受到负调控。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75.
2
NON-INDUCIBLE MUTANTS OF THE REGULATOR GENE IN THE "LACTOSE" SYSTEM OF ESCHERICHIA COLI.
J Mol Biol. 1964 Apr;8:582-92. doi: 10.1016/s0022-2836(64)80013-9.
3
Selective enrichment of Pseudomonas spp. defective in catabolism after exposure to halogenated substrates.
J Bacteriol. 1981 Jun;146(3):920-7. doi: 10.1128/jb.146.3.920-927.1981.
4
p-Cymene pathway in Pseudomonas putida: selective enrichment of defective mutants by using halogenated substrate analogs.
J Bacteriol. 1980 Aug;143(2):816-24. doi: 10.1128/jb.143.2.816-824.1980.
5
Molecular cloning of TOL genes xylB and xylE in Escherichia coli.
J Bacteriol. 1981 Mar;145(3):1137-43. doi: 10.1128/jb.145.3.1137-1143.1981.
6
Molecular and functional analysis of the TOL plasmid pWWO from Pseudomonas putida and cloning of genes for the entire regulated aromatic ring meta cleavage pathway.
Proc Natl Acad Sci U S A. 1981 Dec;78(12):7458-62. doi: 10.1073/pnas.78.12.7458.
7
Construction of a partial diploid for the degradative pathway encoded by the TOL plasmid (pWWO) from Pseudomonas putida mt-2: evidence for the positive nature of the regulation by the xyIR gene.
Mol Gen Genet. 1980 Jan;177(2):321-8. doi: 10.1007/BF00267445.
8
Control of meta-cleavage degradation of 4-hydroxyphenylacetate in Pseudomonas putida.
J Bacteriol. 1981 Sep;147(3):844-50. doi: 10.1128/jb.147.3.844-850.1981.
9
Mutants defective in isomerase and decarboxylase activities of the 4-hydroxyphenylacetic acid meta-cleavage pathway in Pseudomonas putida.
J Bacteriol. 1980 May;142(2):480-5. doi: 10.1128/jb.142.2.480-485.1980.
10
Physical and functional mapping of RP4-TOL plasmid recombinants: analysis of insertion and deletion mutants.
J Bacteriol. 1980 Oct;144(1):222-31. doi: 10.1128/jb.144.1.222-231.1980.
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