Johnson B F, Stanier R Y
J Bacteriol. 1971 Aug;107(2):468-75. doi: 10.1128/jb.107.2.468-475.1971.
The range of aromatic compounds that support the growth of Alcaligenes eutrophus has been determined, and the pathways used for the dissimilation of these substrates have been explored, largely by enzymatic analyses. The beta-ketoadipate pathway operates in the dissimilation of benzoate and p-hydroxybenzoate; the genetisate pathway, in the dissimilation of m-hydroxybenzoate; and the meta cleavage pathway, in the dissimilation of phenol and p-cresol. l-Tryptophan is oxidized via anthranilate; but the metabolic fate of anthranilate was not established. The metabolism of the three stereoisomers of muconic acid was also examined.
已确定支持嗜碱产碱菌生长的芳香族化合物范围,并主要通过酶分析探索了这些底物异化所使用的途径。β-酮己二酸途径在苯甲酸和对羟基苯甲酸的异化中起作用;龙胆酸途径在间羟基苯甲酸的异化中起作用;间位裂解途径在苯酚和对甲酚的异化中起作用。L-色氨酸通过邻氨基苯甲酸氧化;但邻氨基苯甲酸的代谢归宿尚未确定。还研究了粘康酸三种立体异构体的代谢。