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评估痴呆症的临床方法比较。

A comparison of clinical methods for assessing dementia.

作者信息

Eastwood M R, Lautenschlaeger E, Corbin S

出版信息

J Am Geriatr Soc. 1983 Jun;31(6):342-7. doi: 10.1111/j.1532-5415.1983.tb05744.x.

Abstract

General practice physicians and clinical specialists use various methods for assessing dementia, including the Mental State Questionnaire (MSQ), Face-Hand Test (FHT), Dementia Rating Scale (DRS), tests for developmental reflexes and focal neurologic signs, and examination for evidence of clinical depression, stroke, or other physical health problems. In order to determine how these various methods concur, a sample of elderly persons living in the community were evaluated on eight indices. When MSQ scores were used as criteria, the DRS and FHT concurred with classification of impairment in 76 per cent and 45 per cent of cases, respectively. Positive focal signs and developmental reflexes were significantly related to cognitive impairment but were not common features in this sample. Physical health, drug use, and demographic variables did not appear to be related to cognitive function. Although dysphoric mood was related to cognitive impairment, pseudodementia was not identified. After one year the subjects were retested with the MSQ and the DRS; 14 per cent and 20 per cent, respectively, had improved, indicating a lack of predictive validity of these measures. Results are discussed in the context of the utility of clinical methods for screening and staging cognitive impairment, and recommendations are made regarding a standardized battery.

摘要

全科医生和临床专科医生使用多种方法评估痴呆症,包括精神状态问卷(MSQ)、面手试验(FHT)、痴呆评定量表(DRS)、发育反射和局灶性神经体征测试,以及检查是否存在临床抑郁症、中风或其他身体健康问题的证据。为了确定这些不同方法的一致性,对一组居住在社区的老年人在八项指标上进行了评估。以MSQ分数作为标准时,DRS和FHT分别在76%和45%的病例中与损伤分类一致。阳性局灶性体征和发育反射与认知障碍显著相关,但在该样本中并非常见特征。身体健康、药物使用和人口统计学变量似乎与认知功能无关。虽然烦躁情绪与认知障碍有关,但未发现假性痴呆。一年后,对受试者再次进行MSQ和DRS测试;分别有14%和20%的受试者情况有所改善,表明这些测量方法缺乏预测效度。在临床方法用于筛查和分期认知障碍的效用背景下对结果进行了讨论,并就标准化测试组合提出了建议。

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