Jones C T, Robinson J S
J Dev Physiol. 1983 Apr;5(2):77-87.
Fetal growth rate in sheep has been reduced by removal of endometrial caruncles prior to conception. Fetuses were studied between 120-140 days. When small they had much higher plasma catecholamine concentrations than normal which was closely related to plasma pH and PaO2. The increase was predominantly of noradrenaline. During hypoxia, caused by giving ewes 9% O2 and 3% CO2 in N2 to breathe, plasma catecholamine concentrations in small fetuses rose further to levels approximately three times those in normal-sized fetal sheep. Again the increase was predominantly of plasma noradrenaline. During hypoxia the cardiovascular and metabolic responses of the small fetuses were correlated closely with the changes in plasma noradrenaline.
在受孕前切除子宫内膜肉阜会降低绵羊的胎儿生长速率。在120至140天之间对胎儿进行了研究。当胎儿较小时，其血浆儿茶酚胺浓度比正常情况高得多，这与血浆pH值和动脉血氧分压密切相关。增加的主要是去甲肾上腺素。在给母羊吸入含9%氧气、3%二氧化碳和氮气的混合气体导致缺氧期间，小胎儿的血浆儿茶酚胺浓度进一步上升至约为正常大小胎儿绵羊的三倍。同样，增加的主要是血浆去甲肾上腺素。在缺氧期间，小胎儿的心血管和代谢反应与血浆去甲肾上腺素的变化密切相关。
