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关于酯酶D和乙二醛酶I的多态性及其法医学应用(作者译)

[About the polymorphisms of esterase D and glyoxalase I and their forensic application (author's transl)].

作者信息

Brinkmann B, Püschel K

出版信息

Z Rechtsmed. 1978 Jul 27;81(3):181-90.

PMID:685499
Abstract

Phenotypes of esterase D and glyoxalase I were determined electrophoretically in samples from Northern Germany. Gene frequencies: EsD1 = 0,889 (n = 1430), GLO1 = 0,415 (n = 865). The data of 295 (EsD) and 153 (GLO) mother/child combinations were in full accordance with the genetic model of two codominant alleles at an autosomal locus. Esterase D typing has proved successful in bloodstains up to three weeks old. The forensic scope of serological systems is discussed intensively. According to our own data and the results presented in the literature esterase D and glyoxalase I have proved to be useful additional markers for use in cases of disputed paternity.

摘要

在来自德国北部的样本中,通过电泳法测定了酯酶D和乙二醛酶I的表型。基因频率:EsD1 = 0.889(n = 1430),GLO1 = 0.415(n = 865)。295对(EsD)和153对(GLO)母婴组合的数据完全符合常染色体位点上两个共显性等位基因的遗传模型。酯酶D分型已证明在长达三周的陈旧血迹中是成功的。深入讨论了血清学系统的法医应用范围。根据我们自己的数据以及文献中呈现的结果,酯酶D和乙二醛酶I已被证明是用于亲子鉴定案件的有用的额外标记物。

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