Rozen D, Bracamonte M, Sergysels R
Respiration. 1983 May-Jun;44(3):197-203. doi: 10.1159/000194549.
We compared airway resistances (Raw, body plethysmograph) and total pulmonary resistance at 4 and 24 Hz (RRS 4 Hz, 24 Hz) as well as the resonant frequency (RF), both in normals and in patients with airway obstruction. Bronchodilatation (n = 38) was the best evaluated by the induced changes in RRS 4 Hz and RF. However, the importance of change of RRS 4 Hz was poorly correlated with the change in Raw. Bronchial challenge test with histamine and DPT was again the best evaluated by RRS 4 Hz and RF with maximal changes observed for the latter. Normal ranges for Raw, RRS 4 Hz and RF were computed (n = 41). For all patients studied (n = 42) concordance for abnormality was good but poor for normality. From this we conclude that the oscillation technique is a different approach for the evaluation of airway obstruction and that RRS 4 Hz or RF are easy and accurate measurements to follow during bronchodilatation and bronchoconstriction tests.
我们比较了正常人和气道阻塞患者在4赫兹和24赫兹时的气道阻力(体描仪测得的气道阻力)和总肺阻力(4赫兹、24赫兹时的呼吸阻力系统)以及共振频率(RF)。支气管扩张(n = 38)通过4赫兹时呼吸阻力系统和共振频率的诱导变化评估效果最佳。然而,4赫兹时呼吸阻力系统的变化与气道阻力的变化相关性较差。组胺和双倍剂量组胺的支气管激发试验同样通过4赫兹时呼吸阻力系统和共振频率评估效果最佳,后者观察到的变化最大。计算了气道阻力、4赫兹时呼吸阻力系统和共振频率的正常范围(n = 41)。对于所有研究的患者(n = 42),异常的一致性良好,但正常的一致性较差。由此我们得出结论,振荡技术是评估气道阻塞的一种不同方法,并且4赫兹时呼吸阻力系统或共振频率是支气管扩张和支气管收缩试验中易于且准确的监测指标。