Waddell W J, Marlowe C
Science. 1983 Jul 1;221(4605):51-3. doi: 10.1126/science.6857261.
Oral administration of ethanol, n-butanol, or t-butanol to mice 20 minutes before injection of carbon-14-labeled nitrosonornicotine inhibited the localization of radioactivity in bronchial and salivary duct epithelium and in the liver. Localization of radioactivity in the nasal epithelium and esophagus was not significantly reduced. These alcohols therefore may selectively inhibit tumor formation in three of the five sites where this carcinogen typically acts.
在给小鼠注射碳 - 14标记的亚硝基去甲烟碱前20分钟经口给予乙醇、正丁醇或叔丁醇，可抑制放射性在支气管和唾液腺导管上皮以及肝脏中的定位。放射性在鼻上皮和食管中的定位没有显著降低。因此，这些醇类可能会选择性地抑制这种致癌物通常作用的五个部位中的三个部位的肿瘤形成。
