Puschmann M, Schmersahl P
Z Hautkr. 1983 Mar 15;58(6):410-6.
In 20 volunteers, we were able to demonstrate experimentally that side-effects of anthralin application on healthy skin development of erythema and pigmentation, can be significantly reduced in a short contact therapy, in comparison to a longterm treatment. The oxydation products 1.8-dihydroxy-9.10-anthraquinone and 10.10'-dimer which are considered the main impurities of anthralin do not cause any irritation on healthy skin.
在20名志愿者中，我们通过实验证明，与长期治疗相比，短期接触疗法可显著降低蒽林应用于健康皮肤时产生的红斑和色素沉着等副作用。被认为是蒽林主要杂质的氧化产物1,8-二羟基-9,10-蒽醌和10,10'-二聚体对健康皮肤不会造成任何刺激。
