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“输血后乙型肝炎”这一术语按其传统意义使用是否仍然合理?

Is the use of the term 'posttransfusion hepatitis type B' in its conventional sense still justifiable?

作者信息

Sugg U, Erhardt S, Morgenroth T, Flehmig B

出版信息

Vox Sang. 1983;44(5):305-11. doi: 10.1111/j.1423-0410.1983.tb04487.x.

Abstract

We have investigated 8 cases of clinically manifest hepatitis type B said to be posttransfusion hepatitis that have become known in the years 1978-1981. Paired samples of serum from all 54 blood donors implicated have been drawn at the time of the donation in question as well as a few months later. Only 1 donor, negative for HBsAg but positive with high titer for anti-HBc, could have been a possible source of infection. There is strong evidence that this person is a chronic low level carrier. In the case of 2 other patients transmission of hepatitis by clotting factors from pooled plasma cannot be denied. Regarding the remaining 5 cases, there is no hint whatsoever for a causal connection between blood transfusion and hepatitis type B.

摘要

我们对1978年至1981年间发现的8例临床表现为乙型肝炎的所谓输血后肝炎病例进行了调查。对所有54名涉及的献血者,在献血时以及几个月后采集了配对的血清样本。只有1名献血者,乙肝表面抗原(HBsAg)阴性,但抗乙肝核心抗体(anti-HBc)高滴度阳性,可能是感染源。有强有力的证据表明此人是慢性低水平携带者。对于另外2例患者,不能排除由混合血浆中的凝血因子传播肝炎的可能性。至于其余5例,没有任何迹象表明输血与乙型肝炎之间存在因果关系。

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